non ionising radiation in medicine

Definition of non-ionizing radiation Non-ionizing radiation in this document refers to electromagnetic radiation and fields with a photon energy lower than 10 eV, corresponding to frequencies lower than 3 PHz (3 × 10 15 Hz) and wavelengths longer than 100 nm. UV radiation is generally classified as non-ionizing radiation; however, in Figure 9.5, it appears to be on the cusp of non-ionizing and ionizing radiation. Lasers not intended for medical use (and misused medical lasers) can cause irreparable retinal damage and severe burns. In particular, they are concerned about radiofrequency (RF) emissions from […] J. Miyakoshi, T. Shigemitsu, in Comprehensive Biomedical Physics, 2014. Ionizing radiation is a classical mutagen witch can increase chromosomal aberration, the frequencies of chromatin exchange and DNA double-strand breaks. NIR is electromagnetic energy ranging from Extremely Low Frequency (ELF) waves right the way up to Ultraviolet (UV). Since then, many books have been written in the past half century on the characteristics and theory of TL in substantial detail, for example, by Horowitz in 1984; McKeever, Moscovitch, and Townsend in 1995; and Chen and Pagonis in 2011. Relative spectral effectiveness for ultraviolet exposure. First of all, in order to structure this essay, an index will be included, explaining what is to be discussed on it and the order of it: – What is non-ionizing radiation? Ultraviolet light is non-ionizing radiation on the electromagnetic spectrum between visible light and X-rays. Krishnansu S. Tewari M.D., in Clinical Gynecologic Oncology (Seventh Edition), 2007. Thermoluminescence (TL) also called as thermally stimulated luminescence refers to a process in which a solid, usually in crystalline form, emits light while being heated following excitation. Other studies about workers exposed to ionizing radiation failed to confirm these finding. The central location of the aneurysm seen in Figure 2.2C confirmed that the optic chiasm was being compressed, as indicated by the patient's symptoms of peripheral blurred vision and abnormalities (bitemporal hemianopia) found on visual field testing (Chigbu, 2003). For those wishing an even greater mental challenge and extended physical insights, the readers are referred to Bräunlich. Human can be exposed to two types of radiation: non-ionizing radiations via phone, computer, radio and so one or ionizing radiations via medical X-rays or radioactive source. For example, exposition to magnetic field ≥ 1.6 mG increases the risk of poor semen quality and the risk increases with exposure duration in a dose-dependent manner. As a function of the frequency, in general, limits are based on the potential of low frequency electric and magnetic fields, as well as RF radiation, to cause illness or injury through, respectively, the induction of currents or the heating of body tissues. As these weapons incapacitate normal muscle function, they are widely used by police forces on potentially dangerous individuals to make it easier to arrest or restrain them. This technique provides excellent visualisation of anatomical detail, particularly the difference between grey and white matter. New Guideline of the International Commission on Non-ionizing Radiation Protection (ICNIRP) is working out the international guideline for nonionizing radiation, including static fields and ELF and RF fields. The non-ionising imaging theme also encompasses some treatment modalities which are supported by clinical scientists, including ultra violet treatments for skin conditions and laser surgery. Radiations are another physical agents affecting reproduction in male. ICNIRP is closely related to the EMF project of the WHO. Radio frequencies, microwaves, and visible and ultraviolet light are forms of non-ionizing radiation. Gamma rays, x-rays, photons) travel through a medium or space.Radioactivity is the spontaneous nuclear transformation that results in the formation of new elements. Potential injury at the cellular level in MRI may result from exposure to high static magnetic fields. After the EHC for ELF was published, ICNIRP reconsidered the previous international guideline (1998) for time-varying electric and magnetic fields (1 Hz to 100 kHz) and published new guidelines (ICNIRP Guidelines, 2010). However, this can lead to DNA mutations in other cells that survive the radiation, which may eventually lead to the development of a second cancer. I. Eliyahu, in Encyclopedia of Spectroscopy and Spectrometry (Third Edition), 2017. Non-ionising radiation is found at the long wavelength end of the spectrum and may have enough energy to excite molecules and atoms causing then to vibrate faster.This is very obvious in a microwave oven where the radiation causes water molecules to vibrate faster creating heat. Populations occupationally exposed to ionizing radiation have less good sperm parameters with an increase of sperm DNA fragmentation. Claudius Regaud shown in 1977 that radon, a chemical element witch produce ionizing radiation, induces spermatogonia cell death and ram sterilization (Regaud, 1977). ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. URL: https://www.sciencedirect.com/science/article/pii/B9780123864543006035, URL: https://www.sciencedirect.com/science/article/pii/B9780123864543006436, URL: https://www.sciencedirect.com/science/article/pii/B9780123743671000240, URL: https://www.sciencedirect.com/science/article/pii/B9780124157668000094, URL: https://www.sciencedirect.com/science/article/pii/B9780444536327010042, URL: https://www.sciencedirect.com/science/article/pii/B9780323039789500198, URL: https://www.sciencedirect.com/science/article/pii/B9780122265709501058, URL: https://www.sciencedirect.com/science/article/pii/B9780723432852500061, URL: https://www.sciencedirect.com/science/article/pii/B9780128012383643878, URL: https://www.sciencedirect.com/science/article/pii/B9780124095472120967, Encyclopedia of Toxicology (Third Edition), Hayes' Handbook of Pesticide Toxicology (Third Edition), Theodore H. Tulchinsky MD, MPH, Elena A. Varavikova MD, MPH, PhD, in, New Guideline of the International Commission on, Clinical Gynecologic Oncology (Seventh Edition), Both ultrasonography imaging and MRI form images using, Medical diagnosis of neurological conditions, Physical Management in Neurological Rehabilitation (Second Edition), Encyclopedia of Reproduction (Second Edition), Thermoluminescence Theory and Analysis: Advances and Impact on Applications, Encyclopedia of Spectroscopy and Spectrometry (Third Edition), Thermoluminescence (TL) also called as thermally stimulated luminescence refers to a process in which a solid, usually in crystalline form, emits light while being heated following excitation. At a Glance. Copyright © 2020 Elsevier B.V. or its licensors or contributors. 6.- http://es.wikipedia.org/wiki/Radiacion_no_ionizante Ionic or non-ionic, iodinated intravenous contrast media used in CT appear to be safe for the fetus; however, only animal studies have been performed using iodinated contrast agents. It provides an important adjunct to sanitation and good manufacturing practices to reduce morbidity and mortality associated with foodborne diseases, even in industrialized countries. 1,2 However, it is important to note that all major responsible authorities believe it prudent to … The source might be infrared, visible, or ultraviolet; gas discharge, arc, incandescent, or laser. Deterministic effects appear only if the dose is above the thre… Microwave exposures at high levels can damage vulnerable tissues, but the level of dangerous exposure has not yet been conclusively determined. Non-ionizing radiation is considered a possible human carcinogen, primarily due to concerns about childhood leukemia and brain tumors. This kind of radiation is associated with excess exposure to the sun, which in addition to these skin cancers, causes skin and eye burns, cataracts, reduced immunity, and damage to blood vessels. This shows that after developing guidelines for occupational exposure, the calculation for the general public included an additional safety factor. Gadolinium is a category C drug. Organizations such as the ICNIRP provide recommendations for exposure to UV radiation. MEDICAL APPLICATIONS, SPECT IMAGING AND MAIN MEDICAL APPLICATIONS, CANCER STEM CELLS AND RADIATION TREATMENT, OXIDATIVE STRESS AND RESPONSE TO RADIATION, NON-IONIZING RADIATION EXPOSURE: SHORT TERM EFFECTS, SCREENING METHODS IN THE EARLY DIAGNOSIS OF CANCER, RADIOSENSITIVITY AND RADIORESISTANCE OF TUMOURS, TUMORAL GROWING PARAMETER: DUPLICATION TIME, THE ROLE OF TELOMERES IN PREDICTING INDIVIDUAL RADIOSENSITIVITY OF PATIENTS WITH CANCER IN THE ERA OF PERSONALIZED RADIOTHERAPY, TARGETING A CORNERSTONE OF RADIATION RESISTANCE: CANCER STEM CELL. Many of these light sources are very intense or bright and can cause serious and permanent eye damage. The risks of IR incurred at diagnostic imaging levels are presumptive and based on the 'linear / no lower threshold' (LNLT) model and extrapolated from data collected after the atomic bomb explosions in Japan. This is rapidly becoming an essential part of public health protection from foodborne disease in the USA and internationally, although public acceptance is still problematic. In 2012, both the American Academy of Pediatrics and the Government Accounting Office asked the FCC to review their standards established in 1996. Non-ionizing radiation includes visible and non-visible (ultraviolet and infrared) light, lasers, ultrasound, and radiofrequency radiation. Ionizing radiation is a form of energy that acts by removing electrons from atoms and molecules of materials that include air, water, and living tissue. ionising radiation in medicine can be considered as safe for patients as well as for occupational exposed workers. Some of the terminology and techniques can be confusing, e.g., luminance versus illuminance with each of these requiring a specific dosimeter for measurement purposes. NIR is electromagnetic energy ranging from Extremely Low Frequency (ELF) waves right the way up to Ultraviolet (UV). Radiation exists all around us, from both natural and manmade sources, and is in two forms: ionizing and non-ionizing radiation. Imaging procedures are medical tests that allow doctors to see inside the body … In contrast, ionizing radiationhas a higher frequency and shorter wavelength than … 4.- http://www.medicallightassociation.com/?q=node/69 Radio frequencies and microwaves can cause serious burns that show up as a small hole in the skin but cause a larger damaged volume beneath the skin. Each of these has a unique set of requirements for accurate measurement and each requires specially designed measurement tools. Non Ionising Radiation as a Non Chemical Strategy in Regenerative Medicine: Ca 2+-ICR “In Vitro” Effect on Neuronal Differentiation and Tumorigenicity Modulation in NT2 Cells Mario Ledda , 1 Francesca Megiorni , 2 Deleana Pozzi , 1, 2 Livio Giuliani , 3 Enrico D’Emilia , 3 Sara Piccirillo , 1 Cristiana Mattei , 1 Settimio Grimaldi , 1 and Antonella Lisi 1, * HIPOFRACCIONAMIENTO EN RADIOTERAPIA. We define non-ionizing radiation as any kind of electromagnetic radiation that does not carry enough energy to ionize atoms or molecules, not removing any electrons but rather making them vibrate, thus rising the body’s temperature. When discussing different degrees of radiation energy, the issue of both lasers and tasers arises. Radio frequencies and microwaves can cause serious burns that show up as a small hole in the skin but … Because of their potential for misuse and danger, legal restrictions and caution in use are imperative. They are also used for military, medical, and surgical purposes, skin treatments, hair removal, and in research. J.R. Salvatore, in Encyclopedia of Toxicology (Third Edition), 2014. Ionising radiation can also ionise atoms in human cells. Each glow peak can, ideally, be associated with a particular electron or hole trapping center (TC). We use ionising radiation in medicine for diagnostics and treatment, in industry for level or density measurements or non-destructive testing, in research for labelling, microscopy, etc. In contrast, ionizing radiation, which does have the energy to remove electrons from the atoms or/and molecules of the bodies it strikes. TL seems to have been discovered by Robert Boyle who, in 1663, described to the Royal Society one of the first accounts of TL in which he described heating a diamond with the words “I also brought it to some kind of glimmering light, by taking it into bed with me, and holding it a good while upon a warm part of my naked body.” The intensive study of TL started in the first half of the 20th century. ICNIRP guidelines for limiting the development of human health problems related to exposure to NIEMR are accepted by many countries and decision-making entities. If the laser burn affects peripheral vision, this will have minimal or no effect on vision; however, if the fovea is exposed to a laser beam, reading vision may be destroyed. Lasers (an acronym for light amplification by stimulated emission of radiation) are used in many electrical devices, and play an important role in law enforcement. For skin protection, ICNIRP recommends weighted exposures below 30 J m−2 for the most sensitive nonpathologic skin phototypes. Other associated risks may be hyperthermia, causing the tissues to overheat and get damaged. Non-ionizing (or non-ionising) radiation refers to any type of electromagnetic radiation that does not carry enough energy per quantum (photon energy) to ionize atoms or molecules—that is, to completely remove an electron from an atom or molecule. G. Rider, ... D. Stool, in Encyclopedia of Toxicology (Third Edition), 2014. Non-Ionizing Radiation. Tasers are characterized as weapons that function by use of electric currents, which stun and cause temporary debilitation. The new guidelines have changed considerably from the 1998 international guidelines. Applications in Medicine, Image Generation by Positron Emission Tomography (PET), Crosstalk between telomere maintenance and radiation effects: A key player in the process of radiation-induced carcinogenesis, Targeting DNA double-strand break signalling and repair: recent advances in cancer therapy, Oxidative Stress and Skin Cancer: An Overview. In addition, heating can result from energy deposited by radiofrequencies used to generate the pulse sequences. Ionising radiation is used in medicine in 3 ways: diagnostic radiology, which uses x-ray machines to obtain images of the inside of the patient’s body Radio frequencies, microwaves, and visible and ultraviolet light are forms of non-ionizing radiation. Without further investigation, it is difficult for entities like ICNIRP to produce recommendations on exposure limits. The reference level of the intermediate-frequency fields (1–100 kHz) was also reduced four times from the previous levels. Such burns heal very slowly and have a high probability of becoming infected. Non-radioactive, non-ionising radiation for safe paediatric imaging September 13, 2018 E.M. Sevick and J.C. Rasmussen from The University of Texas Health Science Center, The Brown Foundation Institute of Molecular Medicine discuss non-radioactive, non-ionising radiation for safe, paediatric imaging The known danger to humans of absorption of electromagnetic energy is heating and electric current induction, and guidelines usually reflect those endpoints. Excessive use of magnetic resonance imaging (MRI), computed tomography (CT) scans, airport total body scanners and tasers may also contribute to excess radiation exposure, as may the use of cell phones by children as well as adults. Aurore Gely-Pernot, in Encyclopedia of Reproduction (Second Edition), 2018. Carcinoma in situ and neoplasic invasion, Combinated radiotherapy and chemotherapy in the treatment of cancer, Treatment of Cancer with Radiation Theraphy: Aims, Principles and Indications, Introduction to DNA damage response (DDR), Risk from non-ionizing radiation exposure, Radiotherapy and the tumor stroma: the importance of dose and fractionation, Management of biochemical recurrence in prostate adenocarcinoma, Dose Fractionation Radiotherapy: Conventional, Hypo and Hyperfractionation, Low-dose radiation hyper-radiosensitivity in multicellular tumour spheroids, High-grade Gliomas - Multidisciplinary Approach, Book: "Clinical Radiobiology Fundamentals", The novel HDAC inhibitor NDACI054 sensitizes human cancer cells to radiotherapy, BPH (benign prostate hyperplasia) treatment, Fluorescence tomographic imaging (Near IR). According to the US Department of Justice, the use of tasers by law enforcement officials was adopted in an effort to provide stronger control over problematic or aggressive suspects, while resulting in less severe injuries. 3.- http://men.webmd.com/prostate-enlargement-bph/transurethral-microwave-therapy-tumt-for-benign-prostatic-hyperplasia radiation (IR) and non-ionizing radiation (NIR) and their applications in modern medicine. mechanical) effects may occur through motion initiated by the ultrasonic. They are long-length, low-frequency and low-energy waves. Low-dose irradiation is used in the production, processing, and handling of foods to prevent food hazards, and is widely supported by professional organizations. Some of the relevant guidelines are shown in Table 4. They are both increasingly used in various fields for a myriad of purposes. INHIBITION OF BOTH EGFR AND IGF1R SENSITIZED PROSTATE CANCER CELLS TO RADIATION BY SYNERGISTIC SUPPRESSION OF DNA HOMOLOGOUS RECOMBINATION REPAIR, Treatment of Recurrent Basal Cell Carcinoma. The principle effect is a burn of some type. Radiation and Environment (PHIRE) and British Society for Ecological Medicine (BSEM) 2020 Consensus Statement of UK and International Medical and Scientific Experts and Practitioners on Health Effects of Non-Ionising Radiation (NIR) Author: Dr. Erica Mallery-Blythe Release date: 10/11/2020 (Signed by groups representing > 3500 medical doctors) Superseding CT scanning countries will accept the new guidelines have changed considerably the. 2012, both the wavelength and the exposure limits will be reconsidered in country... And brain tumors: optic and some electromagnetic fields, such as those induced by microwave or frequencies! Gely-Pernot, in 1927, Wick reported on the TL of X-ray irradiated and. 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